Cellon Clinic

Stem Cell Lab

Regenerative

What is the Cellon Dermatology Stem Cell Lab?

Stem Cell Research Institute

The Cellon Dermatology Stem Cell Research Institute meets the strict facility
standards and protocols required by Advanced Regenerative Medicine designation,
positioning us as a leader in regenerative medicine. More than a clinical treatment
space, the lab serves as a core R&D hub that explores the fundamental potential
of stem cells and develops optimized therapies, equipped with state-of-the-art
infrastructure that precisely controls every stage—cell isolation, culture, analysis,
and storage.

An advanced analytical system that explores the microscopic world of cells

Our core research instrument, the Olympus Inverted Phase-Contrast
Fluorescence Microscope
, is a high-performance analysis system that
combines phase-contrast imaging—allowing observation of living cells in their
natural state without staining—with fluorescence imaging, which tags specific
molecules or structures to visualize their location and expression with precision.
This lets us monitor subtle morphological changes, differentiation, and cellular
activity in real time, maintaining the highest standard of cell quality control.

We also use a Fluorescence Cell Counter to quantitatively analyze cell
concentration and viability. Fluorescent reagents responsive to specific
wavelengths clearly distinguish living from dead cells, allowing us to verify
the efficacy of treatment-grade stem cells with greater than 99% precision.

Infrastructure for precise cell isolation and preservation

Key Equipment Description
High-speed centrifuge Protocols efficiently separate and concentrate stem cells and growth factors from tissue by density gradient.
Lab workstation All cell-handling steps are performed aseptically in a clean workstation environment that eliminates the risk of contamination at the source.
Cell storage facility Our cryogenic liquid-nitrogen freezer for long-term cell preservation is
the flagship model from Taylor-Wharton, a globally recognized leader in this field.
Uninterruptible power supply Instantly supplies emergency power in the event of an outage, ensuring the continuous operation of
all critical equipment, including the cryogenic freezer.

Setting the standard for advanced regenerative medicine

Built on systematic, science-driven infrastructure that meets Advanced Regenerative
Medicine criteria, the Cellon Dermatology Stem Cell Lab is turning the boundless
potential of regenerative medicine into reality.
Tap the button below to book a consultation.

What are Blood-Derived Stem Cells?

Peripheral Blood Stem Cells, PBSC

A technique that collects and isolates the small population of hematopoietic stem cells (CD34⁺ HSC) circulating
in peripheral blood, then uses them therapeutically. Compared with traditional bone marrow harvesting, it is far less
invasive and can be automated, easing the burden on patients.

How are they collected?

Cellon Dermatology Standard Process
  • Draw 30–240 mL of autologous blood

    No G-CSF or other mobilization agents,
    minimizing the risk of side effects.

  • Centrifugation & fractionation

    Proteins and red blood cells are removed
    to isolate the mononuclear cell layer.

  • CD34⁺ cell purification

    Purified within 90 minutes on MFDS-approved
    equipment → roughly 1–3 × 10⁶ cells
    secured (varies by individual).

  • Immediate administration

    Sterile delivery via either fine intradermal
    microinjection or intravenous infusion, tailored to your needs.

Why does your skin change?

Key Mechanism Description
Regenerative cytokine secretion Releases numerous growth and immune-modulating factors that may help stimulate collagen synthesis and new blood vessel formation
Homing to damaged tissue Migrates to inflamed or hypoxic tissue, taking part directly in local regeneration
Immune & anti-inflammatory effect Polarizes macrophages to ease chronic inflammation

How does it compare with other stem cells?

Category Blood-Derived (PBSC) Adipose-Derived (MSC)
Ease of collection Simple venous blood draw Requires local anesthesia and liposuction
Key markers CD34⁺ · CD45⁺ CD73⁺ · CD90⁺ · CD105⁺
Primary lineage Blood & immune cells Bone, cartilage, fat, dermal fibroblasts
Collagen stimulation Mainly paracrine (secretory) Paracrine + partial direct differentiation
Cell count Relatively low; high-density concentration needed Larger yields, easy to expand in culture
  • Procedure Benefits

    Improved skin elasticity & reduced wrinkles: reported increase in collagen density
    Accelerated scar & wound healing: faster wound contraction, reduced pigmentation
  • Safety & Legal Standards

    Because autologous cells are used, the risk of immune rejection or GVHD is markedly low.
    Under the Advanced Regenerative Medicine and Bio-pharmaceutical Act, our clinic is a Ministry of Health and Welfare designated Advanced Regenerative Medicine Provider.
  • Cellon Dermatology PBSC
    Program Highlights

    01.
    ‘Non-G-CSF' (mobilization-free) draw →
    minimizes fatigue, bone pain and similar side effects
    02.
    90-minute one-stop processing → minimizes drop in cell viability
    03.
    Paired with hyperbaric oxygen therapy* → synergy for early engraftment and oxygen delivery
    04.
    Follow-up monitoring at 1, 3, and 6 months

    * Hyperbaric oxygen (2.0 ATA) + LED regenerative light therapy immediately after the procedure

  • Q1.

    Is it painful?

    The blood draw feels similar to a standard donation, and the topical anesthetic cream makes the injection tolerable for most patients.
  • Q2.

    What about downtime?

    Minor flushing and slight swelling resolve within 1–3 days, so you can wash your face and apply makeup right away.
  • Q3.

    How many sessions are needed?

    Typically one session, followed by a 1–3 month review to decide whether additional treatment is warranted.
  • Q4.

    Any side effects?

    Rare reports include bruising at the injection site and transient warmth;
    no serious complications have been reported to date.

Reboot your skin from within

With Cellon Dermatology's Blood-Derived Stem Cell Lifting & Revital program, you can
lower the burden while unlocking your skin's full regenerative potential.
Tap the button below to book a consultation.

What are Adipose-Derived Cultured Stem Cells?

Adipose Derived Mesenchymal
Stem Cells, AD MSC

The subcutaneous fat in our body acts like a "stem-cell reservoir," brimming with mesenchymal
stem cells (MSCs)
. By safely harvesting these cells and then culturing and concentrating
them in a sterile environment, we obtain a high-purity population that may help drive
skin regeneration and modulate inflammation.

How are cells collected and cultured?

  • Small-volume fat harvest

    Under local anesthesia, we gently
    aspirate just 10–20 mL with
    a fine cannula.

  • Cell isolation

    Centrifugation separates the
    stem-cell-rich
    "stromal vascular fraction (SVF)"
    from the fat tissue.

  • Sterile culture & expansion

    In a GMP-grade facility,
    cell counts are increased
    tens to hundreds of times over 2–3 weeks.

  • Quality & safety testing

    All cultures are confirmed negative for bacteria,
    mycoplasma, and endotoxin, with verified expression
    of marker panels (CD73⁺·CD90⁺·
    CD105⁺)

  • Personalized administration

    Based on your skin condition, we choose
    microinjection, layered delivery,
    or intravenous infusion.

How does it work?

Key Mechanism Description
Paracrine effect Growth factors and cytokines released by stem cells may help stimulate collagen and elastin production.
Immune modulation Rebalances T-cells and macrophages to ease chronic inflammation and stabilize the skin barrier.
Antioxidant & anti-aging Reduces reactive oxygen species (ROS) and defends cells from damage, helping slow signs of aging.
Direct differentiation A portion of cells differentiate into fibroblasts, helping rebuild damaged dermal structure.

What to expect

  • Firmness & lifting

    Higher collagen density helps
    define facial contours.

  • Fine lines & refined pores

    Promotes dermal remodeling for
    a smoother, more refined skin texture.

  • Reduced pigmentation & scars

    Faster tissue recovery may help
    lighten pigmentation and scarring.

  • Calmer dry, sensitive skin

    Anti-inflammatory and hydrating cytokines
    strengthen the skin barrier.

Results and how long they last can vary based on individual skin condition and lifestyle.

  • How safe is it?

    Because autologous tissue is used, the risk of immune rejection or foreign-body reaction is very low.
    All culture steps are performed in a GMP-certified lab to minimize contamination risk.
    Cellon Dermatology is a Ministry of Health and Welfare designated Advanced Regenerative Medicine Provider, and we strictly comply with applicable regulations.
  • Strengths of the Cellon Dermatology AD-MSC Program

    01.
    Small-volume fat harvest minimizes scarring
    02.
    Cell-bank system – one harvest can support multiple sessions
    03.
    Paired with hyperbaric oxygen and LED regenerative light to support early engraftment
    04.
    Quantitative pre- and post-procedure assessment via ultrasound and 3D scanning
  • Q1.

    How long does the procedure take?

    Fat harvest takes about 30 minutes, culture takes 2–3 weeks, and administration takes roughly 20–30 minutes.
  • Q2.

    Is it painful?

    The harvest area is anesthetized locally; injections use numbing cream or a vibration device, so most patients are comfortable.
  • Q3.

    Is recovery long?

    Bruising and swelling at the harvest site fade within 3–5 days; you can return to daily activities right away.
  • Q4.

    How many sessions are needed?

    One administration, then a 6–12 month review to decide whether additional sessions are warranted.
  • Q5.

    Can it be combined with other lifting devices?

    Because Ulthera and Thermage work in different energy ranges, there's a synergistic effect. The exact sequence is decided after consultation.

Let your skin recover on its own.

With Cellon Dermatology's Adipose-Derived Cultured Stem Cell program, awaken your
skin's innate regenerative ability.
Tap the consultation booking button now.

What is Hyperbaric Oxygen Therapy?

HBOT

At Cellon Dermatology, our hyperbaric oxygen therapy is a regenerative treatment
delivered inside a private single-occupant chamber pressurized to more than twice
the normal atmosphere, where you breathe 100% oxygen. The oxygen dissolves deeply
into your blood and skin cells, accelerating recovery and supporting procedure outcomes.

Why pair HBOT with stem cell, PRP, or other regenerative procedures?

  • Changes from increased oxygen
  • Relieves hypoxic stress
  • Supports collagen and elastin production
  • Activates microvasculature and growth factors
  • Strengthens immune and anti-inflammatory response
  • Expected benefits in regenerative procedures
  • Improved survival and engraftment of injected stem cells
  • Faster scar fading and elasticity gains after PRP or laser
  • Less bruising, less swelling, shorter recovery after fat grafting or thread lifting
  • Faster soothing of skin irritation and inflammatory reactions
Key point Adding HBOT immediately after a "cell-based" procedure creates an environment where cells can breathe — making outcomes more pronounced.

Session flow (total 50 minutes)

  • 10 min pressurization

    Similar to an airplane takeoff,
    your ears may briefly feel full.

  • 30 min of 100% oxygen

    Relax and lie back as
    oxygen penetrates deep into your tissues.

  • 10 min depressurization

    Pressure is lowered slowly,
    letting your body adapt naturally.

  • Recommended sessions

    Laser · HIFU: 1–3 sessions
    Autologous fat grafting · stem-cell injection: 3–5 sessions
    Customized based on procedure type and skin condition.
  • What makes Cellon Dermatology's HBOT different

    01.
    Regen-Combo Protocol Stem cells, PRP, and laser linked with HBOT in one space to maximize synergy
    02.
    Single-occupant chamber Guarantees privacy and minimizes external infection risk
    03.
    50-minute focused program Pressurization, treatment, and depressurization all within one hour
    04.
    Dedicated regenerative-medicine team Dermatology specialists and HBOT-certified nurses manage every step with precision

If you have any questions, please reach out to the
Cellon Dermatology Regenerative Medicine Center any time.

In 50 minutes, get the best of both worlds: recovery and results!

What is SELAVE Therapy?

SELAVE

SELAVE is a premium skin-regeneration system built on LIMFU (Low Intensity Multi-Focused Ultrasound)
technology. LIMFU stands for low-energy, multi-focused acoustic waves and delivers an innovative
non-thermal regenerative mechanism that sets itself apart from conventional lifting devices.

LIMFU vs HIFU — a fundamentally different concept

Category LIMFU (Low Intensity Multi-Focused Ultrasound) HIFU (High Intensity Focused Ultrasound)
Intensity Low-intensity energy High-intensity, focused energy
Energy type Mechanical stimulation via pulsed acoustic waves Thermal energy from ultrasound
Target mechanism Tissue regeneration and remodeling via
mechanotransduction
Coagulative necrosis and thermal damage
of fat cells at high temperatures (above 56°C)
Treatment goal Minimize pain while supporting collagen generation and circulation across the full skin layer Destroy and reduce deep subcutaneous fat

Activating mechanotransduction

  • Cell & growth factor stimulation

    Helps drive proliferation and activation of
    fibroblasts and stem cells.

  • Improved collagen & elasticity

    Meaningfully supports skin elasticity and
    reduces the appearance of fine lines.

  • Relaxed muscle tension & refined contours

    Eases excessive facial muscle tension
    to support a natural lift and refined
    contours.

  • Circulation & fat-layer management

    Stimulates blood and lymphatic microcirculation,
    helping reduce facial lymphedema and
    activate fat metabolism.

SELAVE's Multi-Focus method

SELAVE uses pulsed waves generated by an EM (Electro Magnetic) device
to deliver energy. In particular, the patented Multi-Focus Head technology
maximizes lifting efficiency.
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What is Collagen Regeneration?

Collagen Biostimulation

In modern skin science, treatments that slow or reverse aging by harnessing the
skin's own regenerative ability have become a key approach. Going beyond simply
filling volume with external fillers, collagen biostimulation uses biocompatible
materials to stimulate dermal fibroblasts and trigger new collagen synthesis — a
fundamentally regenerative principle.

How collagen biostimulators work

Stage Description
Initial response The injected material occupies physical space, delivering an initial volume effect.
Cellular stimulation As the material gradually breaks down, it continuously stimulates surrounding fibroblasts.
This triggers a controlled, subacute inflammatory response that may activate cellular activity.
Collagen synthesis Activated fibroblasts increase the production of type I and type III collagen and other extracellular matrix.
Structural improvement Over several months, the newly formed collagen fibers strengthen the skin's structural scaffold, delivering gradual, natural volume restoration, improved elasticity, and refined texture.

Types of collagen biostimulators

With its unique ingredients and mechanism of action,
collagen regeneration delivers distinct clinical characteristics.

A successful outcome starts with an accurate medical assessment of your skin type,
degree of aging, anatomical features, and improvement goals.
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What are Exosomes?

Exosome

Cells, the smallest functional unit of our body, do not exist in isolation — they
constantly exchange signals to keep tissues and organs healthy. The substances
that mediate this precise cell-to-cell communication are
exosomes.

What exosomes can do

  • Activate skin-cell proliferation

    Activates skin cell proliferation,
    helping increase skin density
    and elasticity.

  • Anti-inflammatory action

    Supports the improvement of
    inflammatory skin conditions like
    acne, atopic dermatitis, and dermatitis.

  • Skin barrier restoration

    Stimulates ceramide synthesis —
    a core component of the skin barrier —
    to strengthen the skin's defensive
    capability.

  • Damaged-tissue recovery

    Speeds the recovery of damaged tissue and
    helps relieve redness and
    sensitivity after laser
    procedures.

  • Tone & brightening

    Helps improve pigmentation and
    build a clearer, more even
    skin tone.

Key components of exosomes

  • Growth factors

    Proteins that drive cell growth,
    proliferation, and differentiation

  • Cytokines

    Signaling molecules that
    regulate immune and inflammatory responses

  • Proteins & peptides

    Build cellular structure and
    regulate function

  • Lipids

    Components that form and
    protect cell membranes

  • Nucleic acids

    Genetic information that
    regulates the expression of specific proteins
    to control cellular activity

Through cell-to-cell communication, awaken your skin's foundation

Exosomes are a next-generation anti-aging solution that helps rebuild a depleted
skin environment and reawaken time-weary skin cells, helping them radiate from within.
Tap the button below to book a consultation.

CELLON CLINIC Cheongdam. CELLON CLINIC Cheongdam. CELLON CLINIC Cheongdam. CELLON CLINIC Cheongdam.

Location

Address
37 Seolleung-ro 152-gil, 3F, Gangnam-gu, Seoul
(Cheongdam-dong 90-19)
Parking
Valet parking is available on the 1st floor.
Reservations

Cellon Clinic Guide

Hours
Weekdays10:00 AM – 7:00 PM
Saturday10:00 AM – 4:00 PM
*Closed on Sundays and public holidays